HYDROXYAPATITE

RestrictedCAS 1306-06-57 regulations across 7 markets

HYDROXYAPATITE is a cosmetic ingredient classified as Abrasive. Also known as CAS 1306-06-5. It is regulated in 7 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
1306-06-5

Market Overview — 29 Markets

European Union1
United Kingdom
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe1 regulation
European UnionRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for HYDROXYAPATITE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & OceaniaNo restrictions

No specific restrictions for HYDROXYAPATITE in South Korea, Japan, Taiwan, Australia.

ASEANNo restrictions

No specific restrictions for HYDROXYAPATITE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAERestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #372
Chemical name
Hydroxyapatite
CAS
1306-06-5
Max concentration
(a) 10 % (b) 0,465 %
Product type
(a) Toothpaste (b) Mouthwash
Other conditions
For (a) and (b): Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Only nanomaterials having the following characteristics are allowed: — [composed of] rod-shaped particles of which at least 95,8 % (in particle number) have an aspect ratio less than 3, and the remaining 4,2 % have an aspect ratio not exceeding 4,9; — the particles are not coated or surface modified

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for HYDROXYAPATITE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is HYDROXYAPATITE banned in any country?

HYDROXYAPATITE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on HYDROXYAPATITE in cosmetics?

HYDROXYAPATITE is restricted or has conditions of use in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use HYDROXYAPATITE in cosmetics?

HYDROXYAPATITE is regulated in 7 markets. It has restrictions in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.