TOLUENE-2,5-DIAMINE SULFATE

RestrictedCAS 615-50-912 regulations across 11 markets

TOLUENE-2,5-DIAMINE SULFATE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 615-50-9. It is regulated in 11 markets including UAE, Bahrain, Canada.

Also Known As

CAS Number
615-50-9, 95-70-5

Market Overview — 29 Markets

European Union1
United Kingdom2
United States
California
Maryland
Washington
Canada1
Brazil
South Korea1
Japan
Taiwan1
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe3 regulations
European UnionRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #9a
Chemical name
1,4-Benzenediamine, 2-methyl- 2,5-Diaminotoluene sulphate
CAS
95-70-5 615-50-9
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary (b) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: h
Other conditions
(a) (i) General use (a) (ii) Professional use

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #9a
Chemical name
1,4-Benzenediamine, 2-methyl- 2,5-Diaminotoluene sulphate
CAS
95-70-5 615-50-9
Product type
(b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary (b) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: h
Other conditions
(b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (calculated as free base) or 3,6 % (calculated as sulfate salt)

Source: UK retained EC 1223/2009 Annex III

Americas1 regulation
CanadaRestrictedAnnex Table 2 (Restricted)
Chemical name
Coal tar dye
CAS
615-50-9
Conditions of use
a) Not permitted in the area of the eye as indicated in section 14 of the Cosmetic Regulations. b) In hair dyes as indicated in section 22 of the Cosmetic Regulations. | Warning: On the inner label and the outer label of the cosmetic: "CAUTION: this product contains ingredients that may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dying the eyelashes or eyebrows. To do so may cause blindness." Instructions to the following effect accompany each package of hair dye: The preparation may cause serious inflammation of the skin in some persons, and a preliminary test should always be carried out to determine whether or not special sensitivity exists; and To make the test, a small area of skin behind the ear or on the inner surface of the forearm should be cleansed, using either soap and water or alcohol, and a small quantity of the hair dye, as prepared for use, should be applied to the area and allowed to dry. After 24 hours, the area should be washed gently with soap and water. If no irritation or inflammation is apparent, it is usually assumed that no hypersensitivity to the dye exists. The test should, however, be carried out before each application. On no account should the hair dye be used for dyeing eyebrows or eyelashes as severe inflammation of the eye or even blindness may result."

Source: Health Canada Cosmetic Ingredient Hotlist

East Asia & Oceania2 regulations
South KoreaRestrictedAnnex restricted #M1373
Chemical name
Toluene-2,5-Diamine Sulfate
Conditions of use
* 배합한도 : ∙ 산화염모에 3.6 % ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Restricted Ingredients List #66
Chemical name
1,4-Benzenediamine, 2-methyl-/ 2,5-Diaminotoluene sulphate
CAS
95-70-5/ 615-50-9
Max concentration
2% (以free base計) 3.6% (以sulfate salt計)
Product type
Oxidative hair dye products

Source: TFDA Cosmetics Regulations

ASEANNo restrictions

No specific restrictions for TOLUENE-2,5-DIAMINE SULFATE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAERestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #9a
Chemical name
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
CAS
95-70-5 / 615-50-9
Product type
(a) Products intended for colouring eyelashes (b) Products intended for colouring eyelashes
Conditions of use
(a) To be printed on the label: The mixing ratio. ' Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines (toluenediamines) (a) (i) Do not use to dye eyelashes. (a) (ii) Wear suitable gloves. For professional use only.’ (b) As from 3 March 2018, to be printed on the label: The mixing ratio. ' This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the
Other conditions
(a) (i) General use (a) (ii) Professional use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (cal­culated as free base) or 3,6 % (calculated as sulfate salt)

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for TOLUENE-2,5-DIAMINE SULFATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is TOLUENE-2,5-DIAMINE SULFATE banned in any country?

TOLUENE-2,5-DIAMINE SULFATE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on TOLUENE-2,5-DIAMINE SULFATE in cosmetics?

TOLUENE-2,5-DIAMINE SULFATE is restricted or has conditions of use in UAE, Bahrain, Canada, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use TOLUENE-2,5-DIAMINE SULFATE in cosmetics?

TOLUENE-2,5-DIAMINE SULFATE is regulated in 11 markets. It has restrictions in UAE, Bahrain, Canada, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.