TETRAAMINOPYRIMIDINE SULFATE
TETRAAMINOPYRIMIDINE SULFATE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 5392-28-9. It is regulated in 15 markets including UAE, Bahrain, European Union.
Also Known As
- CAS Number
- 5392-28-9
Market Overview — 29 Markets
Detailed Regulations
Europe4 regulations
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: EC 1223/2009 Annex III
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Product type
- (a) Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions. (c) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experie
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate)
Source: UK retained EC 1223/2009 Annex III
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4 % (calculated as sulfate)
- Product type
- (b) Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Max: (b) 3,4 % (calculated as sulfate) (a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions. (c) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after c
Source: UK retained EC 1223/2009 Annex III
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Product type
- (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions. (c) As from 3 March 2018 , to be printed on the label: The mixing ratio. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experie
- Other conditions
- (c) Professional use
Source: UK retained EC 1223/2009 Annex III
AmericasNo restrictions
No specific restrictions for TETRAAMINOPYRIMIDINE SULFATE in United States, California, Maryland, Washington, Canada, Brazil.
East Asia & Oceania1 regulation
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (a)3.4% (以sulfate計) (b)3.4% (以sulfate計)
- Product type
- (a)Oxidative hair dye products (b)Non-oxidative hair dye products
Source: TFDA Cosmetics Regulations
ASEAN6 regulations
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate / Tetraaminopyrimidine Sulfate
- CAS
- 5392-28-9
- Max concentration
- (b) 3.4%(calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 3.4% (calculated as sulphate) (a) and (b): The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past (a) and (b) Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
GCC6 regulations
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2,4,5,6-Tetraaminopyrimidine sulphate
- CAS
- 5392-28-9
- Max concentration
- (b) 3,4% (calculated as sulphate)
- Product type
- (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products (c) Products intended for colouring eyelashes
- Conditions of use
- (a) To be printed on the label: The mixing ratio. “Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (c) As from 3 March 2018, to be printed on the label: The mixing ratio. “This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hai
- Other conditions
- (a) (c) After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 3,4 % (calculated as sulfate) (c) Professional use
Source: GSO 1943:2024 (based on EU 1223/2009 III)
EAEUNo restrictions
No specific restrictions for TETRAAMINOPYRIMIDINE SULFATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is TETRAAMINOPYRIMIDINE SULFATE banned in any country?
TETRAAMINOPYRIMIDINE SULFATE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on TETRAAMINOPYRIMIDINE SULFATE in cosmetics?
TETRAAMINOPYRIMIDINE SULFATE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use TETRAAMINOPYRIMIDINE SULFATE in cosmetics?
TETRAAMINOPYRIMIDINE SULFATE is regulated in 15 markets. It has restrictions in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
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Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.