QUININE

RestrictedCAS 130-95-024 regulations across 21 markets

QUININE is a cosmetic ingredient classified as Denaturant. Also known as CAS 130-95-0. It is regulated in 21 markets including UAE, Armenia, Australia.

Also Known As

CAS Number
130-95-0

Market Overview — 29 Markets

European Union1
United Kingdom2
United States
California
Maryland
Washington
Canada
Brazil
South Korea2
Japan
Taiwan
Australia2
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia1
Belarus1
Kazakhstan1
Armenia1
Kyrgyzstan1

Detailed Regulations

Europe3 regulations
European UnionRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha., 9R)- and its salts
CAS
130-95-0
Max concentration
(a)0,5 % (as quinine base)
Product type
(a)Hair rinse-off products
Conditions of use
Max: (a)0,5 % (as quinine base)

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha., 9R)- and its salts
CAS
130-95-0
Max concentration
(b)0,2 % (as quinine base)
Product type
(b)Hair leave-on products
Conditions of use
Max: (b)0,2 % (as quinine base)

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for QUININE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania4 regulations
South KoreaRestrictedAnnex restricted #M1117
Chemical name
Quinine and its salts
CAS
130-95-0
Conditions of use
* 배합한도 : ∙ 샴푸에 퀴닌염으로서 0.5% ∙ 헤어로션에 퀴닌염로서 0.2% ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

South KoreaRestrictedAnnex restricted #M1311
Chemical name
Quinine
Conditions of use
* 배합한도 : ∙ 샴푸에 퀴닌염으로서 0.5% ∙ 헤어로션에 퀴닌염로서 0.2% ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

AustraliaRestrictedAnnex Schedule 6 (Poison) #SUSMP Schedule 6
Chemical name
QUININE in cosmetic preparations except
Conditions of use
(a) in rinse-off hair preparations containing 0.5% or less of quinine calculated as free base; or (b) in leave-on hair preparations containing 0.2% or less of quinine calculated as free base.

Source: TGA SUSMP F2026L00060

AustraliaRestrictedAnnex Schedule 7 (Dangerous Poison) #SUSMP Schedule 7
Chemical name
QUININE for veterinary use
Conditions of use
when included in Schedule 5.

Source: TGA SUSMP F2026L00060

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #21
Chemical name
Cinchonan-9-ol, 6'-methoxy- (8.alpha, 9R)-and its salts' / Quinine and its salts
CAS
130-95-0
Max concentration
(a) 0.5% calculated as quinine base (b) 0.2% calculated as quinine base
Product type
(a) Shampoos (b) lotions Hair

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #21
Chemical name
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
CAS
130-95-0
Max concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Product type
(a) Hair rinse-off products (b) Hair leave-on products

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEU5 regulations
RussiaRestrictedAnnex 2 #21
Chemical name
Хинин-9-ол, 6'-метокси-, (8.альфа, 9R) и его соли ((Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- and its salts)
CAS
130-95-0
Max concentration
(a) 0,5 процента в пересчете на свободное основание (b) 0,2 процента (в пересчете на хинин)
Product type
(a) Смываемая продукция для волос (b) Несмываемая продукция для волос

Source: TR CU 009/2011 Annex 2 (Restricted Substances) (Ref 21)

BelarusRestrictedAnnex 2 #21
Chemical name
Хинин-9-ол, 6'-метокси-, (8.альфа, 9R) и его соли ((Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- and its salts)
CAS
130-95-0
Max concentration
(a) 0,5 процента в пересчете на свободное основание (b) 0,2 процента (в пересчете на хинин)
Product type
(a) Смываемая продукция для волос (b) Несмываемая продукция для волос

Source: TR CU 009/2011 Annex 2 (Restricted Substances) (Ref 21)

KazakhstanRestrictedAnnex 2 #21
Chemical name
Хинин-9-ол, 6'-метокси-, (8.альфа, 9R) и его соли ((Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- and its salts)
CAS
130-95-0
Max concentration
(a) 0,5 процента в пересчете на свободное основание (b) 0,2 процента (в пересчете на хинин)
Product type
(a) Смываемая продукция для волос (b) Несмываемая продукция для волос

Source: TR CU 009/2011 Annex 2 (Restricted Substances) (Ref 21)

ArmeniaRestrictedAnnex 2 #21
Chemical name
Хинин-9-ол, 6'-метокси-, (8.альфа, 9R) и его соли ((Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- and its salts)
CAS
130-95-0
Max concentration
(a) 0,5 процента в пересчете на свободное основание (b) 0,2 процента (в пересчете на хинин)
Product type
(a) Смываемая продукция для волос (b) Несмываемая продукция для волос

Source: TR CU 009/2011 Annex 2 (Restricted Substances) (Ref 21)

KyrgyzstanRestrictedAnnex 2 #21
Chemical name
Хинин-9-ол, 6'-метокси-, (8.альфа, 9R) и его соли ((Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- and its salts)
CAS
130-95-0
Max concentration
(a) 0,5 процента в пересчете на свободное основание (b) 0,2 процента (в пересчете на хинин)
Product type
(a) Смываемая продукция для волос (b) Несмываемая продукция для волос

Source: TR CU 009/2011 Annex 2 (Restricted Substances) (Ref 21)

Frequently Asked Questions

Is QUININE banned in any country?

QUININE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on QUININE in cosmetics?

QUININE is restricted or has conditions of use in UAE, Armenia, Australia, Bahrain, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use QUININE in cosmetics?

QUININE is regulated in 21 markets. It has restrictions in UAE, Armenia, Australia, Bahrain, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.