P-PHENYLENEDIAMINE SULFATE
P-PHENYLENEDIAMINE SULFATE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 16245-77-5. It is regulated in 11 markets including UAE, Bahrain, Canada.
Also Known As
- CAS Number
- 106-50-3, 16245-77-5, 624-18-0
Market Overview — 29 Markets
Detailed Regulations
Europe3 regulations
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: EC 1223/2009 Annex III
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: EC 1223/2009 Annex III
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary “ black henna ” tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base For professional use only.
Source: UK retained EC 1223/2009 Annex III
Americas1 regulation
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 16245-77-5
- Max concentration
- b) 3% after dilution with an oxidizer
- Conditions of use
- a) Not permitted in products intended for use on the skin. Additionally see "Coal tar dye". b) Oxidative hair dyes | Warning: b) On the inner label and the outer label of the cosmetic: "CAUTION: This product contains ingredients that may cause skin irritation on certain individuals and a preliminary test according to accompanying directions should first be made. This product must not be used for dying the eyelashes or eyebrows. To do so may cause blindness." Instructions to the following effect accompany each package of hair dye: the preparation may cause serious inflammation of the skin in some persons and a preliminary test should always be carried out to determine whether or not special sensitivity exists; and to make the test, a small area of skin behind the ear or on the inner surface of the forearm should be cleansed, using either soap and water or alcohol, and a small quantity of the hair dye as prepared for use should be applied to the area and allowed to dry. After 24 hours, the area should be washed gently with soap and water. If no irritation or inflammation is apparent, it is usually assumed that no hypersensitivity to the dye exists. The test should, however, be carried out before each application. On no account should the hair dye be used for dyeing eyebrows or eyelashes as severe inflammation of the eye or even blindness may result.
Source: Health Canada Cosmetic Ingredient Hotlist
East Asia & Oceania2 regulations
- Chemical name
- p-Phenylenediamine Sulfate
- Conditions of use
- * 배합한도 : ∙ 산화염모에 3.8 % ∙ 기타 제품에는 사용금지
Source: MFDS Korea Cosmetics Regulation
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3/ 624-18-0/ 16245-77-5
- Max concentration
- 2% (以free base計)
- Product type
- Oxidative hair dye products
Source: TFDA Cosmetics Regulations
ASEANNo restrictions
No specific restrictions for P-PHENYLENEDIAMINE SULFATE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.
GCC12 regulations
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p-Phenylenediamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- (a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows.’ (b) To be printed on the label: The mixing ratio. ‘For professional use only. Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you h
- Other conditions
- (a) General use (b) Professional use For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2 % calculated as free base
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- p- Phenylene-diamine and its salts
- CAS
- 106-50-3 / 624-18-0 / 16245-77-5
- Product type
- Products intended for colouring eyelashes
- Conditions of use
- To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them. Contains phenylenediamines. Wear suitable gloves.” ’
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to eyelashes must not exceed 2 % calculated as free base. For professional use only.
Source: GSO 1943:2024 (based on EU 1223/2009 III)
EAEUNo restrictions
No specific restrictions for P-PHENYLENEDIAMINE SULFATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is P-PHENYLENEDIAMINE SULFATE banned in any country?
P-PHENYLENEDIAMINE SULFATE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on P-PHENYLENEDIAMINE SULFATE in cosmetics?
P-PHENYLENEDIAMINE SULFATE is restricted or has conditions of use in UAE, Bahrain, Canada, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use P-PHENYLENEDIAMINE SULFATE in cosmetics?
P-PHENYLENEDIAMINE SULFATE is regulated in 11 markets. It has restrictions in UAE, Bahrain, Canada, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
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Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.