OXYQUINOLINE

BannedCAS 148-24-325 regulations across 18 markets

OXYQUINOLINE is a cosmetic ingredient classified as Antimicrobial. Also known as CAS 148-24-3. It is regulated in 18 markets including UAE, Bahrain, Brazil.

Also Known As

CAS Number
134-31-6, 148-24-3

Market Overview — 29 Markets

European Union1
United Kingdom2
United States
California
Maryland
Washington
Canada1
Brazil1
South Korea1
Japan
Taiwan1
Australia
Singapore2
Malaysia2
Thailand2
Indonesia2
Vietnam2
Philippines2
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe3 regulations
European UnionBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: EC 1223/2009 Annex II

United KingdomRestrictedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate, except for the uses of the sulphate provided for in entry 51 of Annex III
CAS
148-24-3 134-31-6

Source: UK retained EC 1223/2009 Annex II

United KingdomRestrictedAnnex III #51
Chemical name
Bis(8-hydroxyquinolinium) sulphate
CAS
134-31-6
Max concentration
(0,3 % as base)
Product type
Stabilizer for hydrogen peroxide in rinse-off hair products
Conditions of use
Max: (0,3 % as base)

Source: UK retained EC 1223/2009 Annex III

Americas2 regulations
CanadaRestrictedAnnex Table 2 (Restricted)
Chemical name
8-Hydroxyquinoline and its sulfate
CAS
148-24-3
Max concentration
a) 0.3% b) 0.03%
Conditions of use
a) As stabilizers for hydrogen peroxide in rinse-off hair products b) As stabilizers for hydrogen peroxide in leave-on hair products

Source: Health Canada Cosmetic Ingredient Hotlist

BrazilBannedAnnex RDC_529 #395
Chemical name
Hidroxi-8-quinolina e seu sulfato, exceto os mencionados em outras listas de substâncias
CAS
148-24-3

Source: ANVISA RDC 529

East Asia & Oceania2 regulations
South KoreaBannedAnnex banned #M9
Chemical name
Oxyquinoline

Source: MFDS Korea Cosmetics Regulation

TaiwanBannedAnnex Prohibited Ingredients List #12
Chemical name
Hydroxy-8-quinoline and its sulfate
CAS
148-24-3/ 134-31-6
Product type
hair_dye
Conditions of use
使用於染髮、燙髮產品中,用作Hydrogen peroxide 之安定劑不得超過0.03%(以base計)。
Other conditions
使用於染髮、燙髮產品中,用作Hydrogen peroxide 之安定劑不得超過0.03%(以base計)。

Source: TFDA Cosmetics Regulations

ASEAN12 regulations
SingaporeBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

SingaporeRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesBannedAnnex ACD Annex II (Prohibited) #395
Chemical name
Hydroxy-8-quinoline and its sulphate
CAS
148-24-3
Conditions of use
except for the uses provided for in Annex III, Part 1 No 51

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #51
Chemical name
Quinolin-8-ol and bis (8- hydroxyquinolium) sulphate Oxyquinoline and / Oxyquinoline Sulphate
CAS
148-24-3/134-31-6
Max concentration
(a) 0.3% calculated as base (b) 0.03% calculated as base
Product type
(a) Stabilizer for hydrogen peroxide in rinse-off hair care products. (b) Stabilizer for hydrogen peroxide in non-rinse- off hair products.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAEBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

Saudi ArabiaBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

QatarBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

OmanBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

KuwaitBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

BahrainBannedAnnex II #395
Chemical name
Hydroxy-8-quinoline and its sulphate bis(8-hydroxyquinolinium) sulphate
CAS
148-24-3 [1]
Other conditions
except for the uses of the sulphate provided for in entry 51 of Annex III

Source: GSO 1943:2024 (based on EU 1223/2009 II)

EAEUNo restrictions

No specific restrictions for OXYQUINOLINE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is OXYQUINOLINE banned in any country?

Yes, OXYQUINOLINE is banned in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, Vietnam. Always check current regulations before formulating products for these markets.

What are the restrictions on OXYQUINOLINE in cosmetics?

OXYQUINOLINE is restricted or has conditions of use in Canada, Indonesia, Malaysia, Philippines, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use OXYQUINOLINE in cosmetics?

OXYQUINOLINE is regulated in 18 markets. It is banned in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, Vietnam. It has restrictions in Canada, Indonesia, Malaysia, Philippines, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.