OCTOPAMINE

BannedCAS 104-14-316 regulations across 16 markets

OCTOPAMINE is a cosmetic ingredient classified as Skin Conditioning. Also known as CAS 104-14-3. It is regulated in 16 markets including UAE, Bahrain, Brazil.

Also Known As

CAS Number
104-14-3, 300-62-9

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil1
South Korea1
Japan
Taiwan
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: EC 1223/2009 Annex II

United KingdomBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and are referred to in resolution AP (69) 2 of the Council of Europe
CAS
300-62-9

Source: UK retained EC 1223/2009 Annex II

Americas1 regulation
BrazilBannedAnnex RDC_529 #21
Chemical name
Aminas Simpaticomiméticas que atuam sobre o sistema nervoso central
CAS
300-62-9

Source: ANVISA RDC 529

East Asia & Oceania1 regulation
South KoreaBannedAnnex banned #M231
Chemical name
Octopamine

Source: MFDS Korea Cosmetics Regulation

ASEAN6 regulations
SingaporeBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesBannedAnnex ACD Annex II (Prohibited) #21
Chemical name
Sympathicomimetic amines acting on the central nervous system as defined in ASEAN member States (AMS) local law(s) or regulation(s)
CAS
300-62-9

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAEBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

Saudi ArabiaBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

QatarBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

OmanBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

KuwaitBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

BahrainBannedAnnex II #21
Chemical name
Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
CAS
104-14-3

Source: GSO 1943:2024 (based on EU 1223/2009 II)

EAEUNo restrictions

No specific restrictions for OCTOPAMINE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is OCTOPAMINE banned in any country?

Yes, OCTOPAMINE is banned in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Always check current regulations before formulating products for these markets.

What are the restrictions on OCTOPAMINE in cosmetics?

OCTOPAMINE is banned in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam and has no specific restrictions in other tracked markets.

Can I use OCTOPAMINE in cosmetics?

OCTOPAMINE is regulated in 16 markets. It is banned in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

Screen OCTOPAMINE with your full formula

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.