O-PHENYLPHENOL

RestrictedCAS 90-43-726 regulations across 24 markets

O-PHENYLPHENOL is a cosmetic ingredient classified as Preservative. Also known as CAS 90-43-7. It is regulated in 24 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number
132-27-4, 90-43-7

Market Overview — 29 Markets

European Union1
United Kingdom2
United States
California1
Maryland
Washington
Canada
Brazil1
South Korea1
Japan2
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia1
Belarus1
Kazakhstan1
Armenia1
Kyrgyzstan1

Detailed Regulations

Europe3 regulations
European UnionRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
(a) 0,2 % (as phenol)
Product type
(a) Rinse-off Products
Conditions of use
Max: (a) 0,2 % (as phenol) Avoid contact with eyes

Source: UK retained EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
(b) 0,15 % (as phenol)
Product type
(b) Leave-on products
Conditions of use
Max: (b) 0,15 % (as phenol) Avoid contact with eyes

Source: UK retained EC 1223/2009 Annex V

Americas2 regulations
CaliforniaRestrictedAnnex PROP65
Chemical name
o-Phenylphenol
CAS
90-43-7
Conditions of use
Prop 65 Warning Required: cancer

Source: California Prop 65

BrazilRestrictedAnnex RDC_528 #7
Chemical name
Bifenil-2-ol (o-fenilfenol)
CAS
90-43-7
Max concentration
a) 0,2% (expresso como fenol) em produtos que se enxáguem. b) 0,15% (expresso como fenol) em produtos que não se enxáguem.
Conditions of use
Limitations: Proibidos os sais de o-phenylph enol. | Warnings: Evitar contato com os olhos.

Source: ANVISA RDC 528

East Asia & Oceania4 regulations
South KoreaRestrictedAnnex restricted #M1339
Chemical name
o-Phenylphenol
Conditions of use
* 배합한도 : 페놀로서 0.15%

Source: MFDS Korea Cosmetics Regulation

JapanRestrictedAnnex Appendix 3 (Preservatives) #3-2
Chemical name
o-Phenyl phenol
Max concentration
0.30%
Product type
Leave-on (cosmetics not washed away)

Source: MHLW Standards for Cosmetics (Notification No.331 of 2000)

JapanRestrictedAnnex Appendix 3 (Preservatives) #3-2
Chemical name
o-Phenyl phenol
Product type
Rinse-off (cosmetics washed away after use)

Source: MHLW Standards for Cosmetics (Notification No.331 of 2000)

TaiwanRestrictedAnnex Preservatives List #31
Chemical name
Biphenyl-2-ol, and its salts
CAS
90-43-7/ 132-27-4/ 84145-04-0/ 13707-65-8
Max concentration
0.2 % (以phenol計)

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex VI (Preservatives) #7
Chemical name
Biphenyl-2-ol
CAS
90-43-7
Max concentration
Rinse-off products; 0.2% (as phenol) Leave-on products; 0.15% (as phenol)
Conditions of use
Avoid contact with eyes.

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

Saudi ArabiaRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

QatarRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

OmanRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

KuwaitRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

BahrainRestrictedAnnex V #7
Chemical name
Biphenyl-2-ol; 2-phenylphenol; 2-hydroxybiphenyl, Sodium 2-biphenylate
CAS
90-43-7, 132-27-4
Max concentration
(a) 0,2 % (as phenol (b) 0,15 % (as phenol)
Product type
(a) Rinse-off products (b) Leave-on products
Conditions of use
Avoid contact with eyes.
Other conditions
When o-Phenylphenol and Sodium o-Phenylphenate are used together, the combined concentration (as phenol) shall not exceed 0,2 % in rinse-off and 0,15 % in leave-on products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products.

Source: GSO 1943:2024 (based on EU 1223/2009 V)

EAEU5 regulations
RussiaRestrictedAnnex 4 #7
Chemical name
Бифенил-2-ол
CAS
90-43-7
Max concentration
(a) 0,2 процента в пересчете на фенол (b) 0,15 процента в пересчете на фенол
Product type
(a) Смываемая продукция (b) Несмываемая продукция
Conditions of use
Избегать контакта с глазами

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 7)

BelarusRestrictedAnnex 4 #7
Chemical name
Бифенил-2-ол
CAS
90-43-7
Max concentration
(a) 0,2 процента в пересчете на фенол (b) 0,15 процента в пересчете на фенол
Product type
(a) Смываемая продукция (b) Несмываемая продукция
Conditions of use
Избегать контакта с глазами

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 7)

KazakhstanRestrictedAnnex 4 #7
Chemical name
Бифенил-2-ол
CAS
90-43-7
Max concentration
(a) 0,2 процента в пересчете на фенол (b) 0,15 процента в пересчете на фенол
Product type
(a) Смываемая продукция (b) Несмываемая продукция
Conditions of use
Избегать контакта с глазами

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 7)

ArmeniaRestrictedAnnex 4 #7
Chemical name
Бифенил-2-ол
CAS
90-43-7
Max concentration
(a) 0,2 процента в пересчете на фенол (b) 0,15 процента в пересчете на фенол
Product type
(a) Смываемая продукция (b) Несмываемая продукция
Conditions of use
Избегать контакта с глазами

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 7)

KyrgyzstanRestrictedAnnex 4 #7
Chemical name
Бифенил-2-ол
CAS
90-43-7
Max concentration
(a) 0,2 процента в пересчете на фенол (b) 0,15 процента в пересчете на фенол
Product type
(a) Смываемая продукция (b) Несмываемая продукция
Conditions of use
Избегать контакта с глазами

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 7)

Frequently Asked Questions

Is O-PHENYLPHENOL banned in any country?

O-PHENYLPHENOL is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on O-PHENYLPHENOL in cosmetics?

O-PHENYLPHENOL is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Japan, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use O-PHENYLPHENOL in cosmetics?

O-PHENYLPHENOL is regulated in 24 markets. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Japan, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.