N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL

BannedCAS 66566-48-117 regulations across 16 markets

N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 66566-48-1. It is regulated in 16 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
66566-48-1, 72584-59-9

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea2
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: EC 1223/2009 Annex II

United KingdomBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt, when used as a substance in hair dye products
CAS
72584-59-9/66566-48-1

Source: UK retained EC 1223/2009 Annex II

AmericasNo restrictions

No specific restrictions for N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania3 regulations
South KoreaBannedAnnex banned #M22
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine
CAS
66566-48-1

Source: MFDS Korea Cosmetics Regulation

South KoreaBannedAnnex banned #M705
Chemical name
N-Methoxyethyl-p-Phenylenediamine HCl

Source: MFDS Korea Cosmetics Regulation

TaiwanBannedAnnex Prohibited Ingredients List #274
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt 不得使用於染髮用途化粧品
CAS
72584-59-9/ 66566-48-1

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesBannedAnnex ACD Annex II (Prohibited) #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9/ 6566-48-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAEBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

Saudi ArabiaBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

QatarBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

OmanBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

KuwaitBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

BahrainBannedAnnex II #1226
Chemical name
N-(2-Methoxyethyl)-p-phenylenediamine and its HCl salt
CAS
72584-59-9 / 66566-48-1
Product type
hair dye products

Source: GSO 1943:2024 (based on EU 1223/2009 II)

EAEUNo restrictions

No specific restrictions for N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL banned in any country?

Yes, N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL is banned in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Always check current regulations before formulating products for these markets.

What are the restrictions on N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL in cosmetics?

N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL is banned in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam and has no specific restrictions in other tracked markets.

Can I use N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL in cosmetics?

N-METHOXYETHYL-P-PHENYLENEDIAMINE HCL is regulated in 16 markets. It is banned in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.