MUSK XYLENE

RestrictedCAS 81-15-216 regulations across 16 markets

MUSK XYLENE is a cosmetic ingredient classified as Fragrance. Also known as CAS 81-15-2. It is regulated in 16 markets including UAE, Bahrain, Brazil.

Also Known As

CAS Number
81-15-2

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil1
South Korea1
Japan
Taiwan
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a)1,0 % in fine fragrance(b)0,4 % in eau de toilette(c)0,03 % in other products
Product type
All cosmetic products, with the exception of oral products
Conditions of use
Max: (a)1,0 % in fine fragrance(b)0,4 % in eau de toilette(c)0,03 % in other products

Source: UK retained EC 1223/2009 Annex III

Americas1 regulation
BrazilRestrictedAnnex RDC_530 #90
Chemical name
Almizcle xileno (CAS 8 1-15-2)
CAS
81-15-2
Max concentration
a) 1% em fragrâncias finas b) 0,4% em colônias c) 0,03 % em outros produtos
Product type
Todos os produtos, exceto os produtos para higiene bucal
Conditions of use
Application: Todos os produtos, exceto os produtos para higiene bucal

Source: ANVISA RDC 530

East Asia & Oceania1 regulation
South KoreaRestrictedAnnex restricted #M1286
Chemical name
Musk Xylene
Conditions of use
* 배합한도 : ∙ 향수류 향료원액을 8% 초과하여 함유하는 제품에 1.0%, 향료원액을 8% 이하로 함유하는 제품에 0.4% ∙ 기타 제품에 0.03%

Source: MFDS Korea Cosmetics Regulation

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene / Musk xylene
CAS
81-15-2
Max concentration
(a) 1.0 %in fine fragrance (b) 0.4 %in eau de toilette (c) 0.03 %in other products
Product type
All cosmetic products, with the exception of oral care products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #96
Chemical name
5-tert-Butyl-2,4,6-trinitro-m-xylene
CAS
81-15-2
Max concentration
(a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products
Product type
All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for MUSK XYLENE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is MUSK XYLENE banned in any country?

MUSK XYLENE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on MUSK XYLENE in cosmetics?

MUSK XYLENE is restricted or has conditions of use in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use MUSK XYLENE in cosmetics?

MUSK XYLENE is regulated in 16 markets. It has restrictions in UAE, Bahrain, Brazil, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.