MORPHOLINE
MORPHOLINE is a cosmetic ingredient classified as Buffering. Also known as CAS 110-91-8. It is regulated in 17 markets including UAE, Bahrain, Brazil.
Also Known As
- CAS Number
- 110-91-8, 300-62-9
Market Overview — 29 Markets
Detailed Regulations
Europe3 regulations
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: EC 1223/2009 Annex II
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: EC 1223/2009 Annex II
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: UK retained EC 1223/2009 Annex II
Americas2 regulations
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
- Conditions of use
- Prohibited in cosmetics
Source: Health Canada Cosmetic Ingredient Hotlist
- Chemical name
- Morfolina e seus sais
- CAS
- 110-91-8
Source: ANVISA RDC 529
East Asia & Oceania2 regulations
- Chemical name
- Morpholine
Source: MFDS Korea Cosmetics Regulation
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: MFDS Korea Cosmetics Regulation
ASEAN6 regulations
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
GCC12 regulations
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical prescription and referred to in Resolution AP (69) 2 of the Council of Europe
- CAS
- 300-62-9
Source: GSO 1943:2024 (based on EU 1223/2009 II)
- Chemical name
- Morpholine and its salts
- CAS
- 110-91-8
Source: GSO 1943:2024 (based on EU 1223/2009 II)
EAEUNo restrictions
No specific restrictions for MORPHOLINE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is MORPHOLINE banned in any country?
Yes, MORPHOLINE is banned in UAE, Bahrain, Brazil, Canada, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Always check current regulations before formulating products for these markets.
What are the restrictions on MORPHOLINE in cosmetics?
MORPHOLINE is banned in UAE, Bahrain, Brazil, Canada, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam and has no specific restrictions in other tracked markets.
Can I use MORPHOLINE in cosmetics?
MORPHOLINE is regulated in 17 markets. It is banned in UAE, Bahrain, Brazil, Canada, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
Screen MORPHOLINE with your full formula
Paste your entire ingredient list and get a compliance report across 26 markets — free, no signup.
Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.