METHYLENE DIPHENYL DIISOCYANATE

BannedCAS 101-68-88 regulations across 8 markets

METHYLENE DIPHENYL DIISOCYANATE is a cosmetic ingredient classified as Not Reported. Also known as CAS 101-68-8. It is regulated in 8 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
101-68-8

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: EC 1223/2009 Annex II

United KingdomBannedAnnex II #1533
Chemical name
4,4′-Methylenediphenyl diisocyanate; diphenylmethane-4,4′-diisocyanate [1]
CAS
101-68-8 [1]

Source: UK retained EC 1223/2009 Annex II

AmericasNo restrictions

No specific restrictions for METHYLENE DIPHENYL DIISOCYANATE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & OceaniaNo restrictions

No specific restrictions for METHYLENE DIPHENYL DIISOCYANATE in South Korea, Japan, Taiwan, Australia.

ASEANNo restrictions

No specific restrictions for METHYLENE DIPHENYL DIISOCYANATE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAEBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

Saudi ArabiaBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

QatarBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

OmanBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

KuwaitBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

BahrainBannedAnnex II #1533
Chemical name
4,4'-Methylenediphenyl diisocyanate; diphenylmethane-4,4'-diisocyanate [1]; 2,2'-Methylenediphenyl diisocyanate; diphenylmethane-2,2'-diisocyanate [2]; o-(p-Isocyanatobenzyl)phenyl isocyanate; diphenylmethane-2,4'-diisocyanate [3]; Methylenediphenyl diisocyanate [4]
CAS
101-68-8 [1] 2536-05-2 [2] 5873-54-1 [3] 26447-40-5 [4]

Source: GSO 1943:2024 (based on EU 1223/2009 II)

EAEUNo restrictions

No specific restrictions for METHYLENE DIPHENYL DIISOCYANATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is METHYLENE DIPHENYL DIISOCYANATE banned in any country?

Yes, METHYLENE DIPHENYL DIISOCYANATE is banned in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Always check current regulations before formulating products for these markets.

What are the restrictions on METHYLENE DIPHENYL DIISOCYANATE in cosmetics?

METHYLENE DIPHENYL DIISOCYANATE is banned in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom and has no specific restrictions in other tracked markets.

Can I use METHYLENE DIPHENYL DIISOCYANATE in cosmetics?

METHYLENE DIPHENYL DIISOCYANATE is regulated in 8 markets. It is banned in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.