METHYLCHLOROISOTHIAZOLINONE

RestrictedCAS 26172-55-421 regulations across 20 markets

METHYLCHLOROISOTHIAZOLINONE is a cosmetic ingredient classified as Preservative. Also known as CAS 26172-55-4. It is regulated in 20 markets including UAE, Australia, Bahrain.

Also Known As

CAS Number: 26172-55-4, 2682-20-4, 55965-84-9

Market Overview — 29 Markets

European Union1

United Kingdom2

United States

California

Maryland

Washington

Canada1

Brazil1

South Korea1

Japan1

Taiwan1

Australia1

Singapore1

Malaysia1

Thailand1

Indonesia1

Vietnam1

Philippines1

UAE1

Saudi Arabia1

Qatar1

Oman1

Kuwait1

Bahrain1

Russia

Belarus

Kazakhstan

Armenia

Kyrgyzstan

Detailed Regulations

Europe3 regulations

European UnionRestrictedAnnex V #39

Chemical name: Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate
CAS: 26172-55-4, 2682-20-4, 55965-84-9
Max concentration: 0.0015% (of a mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one
Product type: Rinse-off

Source: EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #39

Chemical name: Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-methylisothiazol-3(2H)-one
CAS: 26172-55-4, 2682-20-4, 55965-84-9
Max concentration: 0,0015 % (of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one)
Product type: Rinse-off products
Conditions of use: Max: 0,0015 % (of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one)

Source: UK retained EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #57

Chemical name: 2-Methyl-2H-isothiazol-3-one
CAS: 2682-20-4
Max concentration: 0,0015 %
Product type: Rinse-off products
Conditions of use: Max: 0,0015 %

Source: UK retained EC 1223/2009 Annex V

Americas2 regulations

CanadaRestrictedAnnex Table 2 (Restricted)

Chemical name: Methylisothiazolinone / Methylchloroisothiazolinone, in combination
CAS: 26172-55-4
Max concentration: b) 0.0015%
Conditions of use: a) Not permitted in leave-on products. b) Rinse-off products Note: MCI is only permitted when present in combination with MI. If MI/MCI is present in a formulation with MI alone, the cumulative, total concentration of MI/MCI and MI may not exceed 0.0015%.

Source: Health Canada Cosmetic Ingredient Hotlist

BrazilRestrictedAnnex RDC_528 #35

Chemical name: Mistura de 5-cloro-2-metil-4-is otiazolina-3-ona e 2-metil-4-isotiazo lina-3-ona com cloreto de magnésio e nitrato de magnésio (3:1)
CAS: 26172-55-4
Max concentration: 0,0015% (de uma mistura em proporções 3:1 de 5-Chloro-2-methyl- isothiazol-3(2H)-on e e 2- Methylisothiazol-3 (2H)-one) em produtos que se enxáguem.
Conditions of use: Limitations: -Proibido em produtos que não se enxáguem (incluindo os lenços umedecidos ). -A utilização da mistura de methylchlor oisothiazoli none e methylisothi azolinone é incompatíve l com a utilização de methylisothi azolinone sozinha em um mesmo produto.

Source: ANVISA RDC 528

East Asia & Oceania4 regulations

South KoreaRestrictedAnnex restricted #M1325

Chemical name: Methylchloroisothiazolinone
Conditions of use: * 배합한도 : ∙ 사용 후 씻어내는 제품에 0.0015% (메칠클로로이소치아졸리논:메칠이소치아졸리논=(3:1)혼합물로서) ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

JapanRestrictedAnnex Appendix 3 (Preservatives) #3-2

Chemical name: Methylchloro isothiazolinone and methyl isothiazolinone solution
Max concentration: 0.10%
Product type: Rinse-off (cosmetics washed away after use)
Conditions of use: Aqueous solution containing 1.0-1.3% 5-chloro-2-methyl-4-isothiazolin-3-one and 0.30-0.42% 2-methyl-4-isothiazolin-3-one

Source: MHLW Standards for Cosmetics (Notification No.331 of 2000)

TaiwanRestrictedAnnex Preservatives List #30

Chemical name: Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)-one and 2-Methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate
CAS: 55965-84-9, 26172-55-4, 2682-20-4
Max concentration: 0.0015 %
Product type: R i nse off products
Conditions of use: Mixture in the ratio 3:1 of 5-Chloro-2-methyl-isothia zol-3(2H)-one and 2- Methylisothiazol-3(2H)-one

Source: TFDA Cosmetics Regulations

AustraliaRestrictedAnnex Schedule 6 (Poison) #SUSMP Schedule 6

Chemical name: METHYLCHLOROISOTHIAZOLINONE except
Conditions of use: (a) in rinse-off cosmetic preparations or therapeutic goods intended for topical rinse-off application containing 0.0015% or less of methylchloroisothiazolinone and methylisothiazolinone in total; or (b) in other preparations that are not intended for direct application to the skin containing 0.1% or less of methylchloroisothiazolinone and methylisothiazolinone in total.

Source: TGA SUSMP F2026L00060

ASEAN6 regulations

SingaporeRestrictedAnnex ACD Annex VI (Preservatives) #39

Chemical name: Mixture of 5-Chloro-2-methyl-isothiazol-3(2H)- one and 2-Methylisothiazol-3(2H)-one (INCI) / Methylchloroisothiazolinone (and) Methylisothiazolinone (9), 2682-20-4, 55965-84-9
CAS: 26172-55-4
Max concentration: 0,0015 %(of a mixture in the ratio 3:1 of 5-chloro- 2- methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one)
Conditions of use: Rinse-off products