ISATIN
RestrictedCAS 91-56-515 regulations across 15 markets
ISATIN is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 91-56-5. It is regulated in 15 markets including UAE, Bahrain, European Union.
Also Known As
- CAS Number
- 91-56-5
Market Overview — 29 Markets
European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan
Detailed Regulations
Europe2 regulations
European UnionRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: EC 1223/2009 Annex III
United KingdomRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1,6 %
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Max: 1,6 % Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colorants can cause severe allergic reactions.
Source: UK retained EC 1223/2009 Annex III
AmericasNo restrictions
No specific restrictions for ISATIN in United States, California, Maryland, Washington, Canada, Brazil.
East Asia & Oceania1 regulation
TaiwanRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Non-oxidative hair dye products
Source: TFDA Cosmetics Regulations
ASEAN6 regulations
SingaporeRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
MalaysiaRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
ThailandRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
IndonesiaRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
VietnamRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
PhilippinesRestricted
- Chemical name
- 1H-Indole-2,3-Dione / Isatin
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
GCC6 regulations
UAERestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
Saudi ArabiaRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
QatarRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
OmanRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
KuwaitRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
BahrainRestricted
- Chemical name
- 1H-Indole-2,3-Dione
- CAS
- 91-56-5
- Max concentration
- 1.6%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’
Source: GSO 1943:2024 (based on EU 1223/2009 III)
EAEUNo restrictions
No specific restrictions for ISATIN in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is ISATIN banned in any country?
ISATIN is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on ISATIN in cosmetics?
ISATIN is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use ISATIN in cosmetics?
ISATIN is regulated in 15 markets. It has restrictions in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
Screen ISATIN with your full formula
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Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.