HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE

BannedCAS 38866-20-523 regulations across 15 markets

HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 38866-20-5. It is regulated in 15 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
110-91-8, 38866-20-5

Market Overview — 29 Markets

European Union2
United Kingdom2
United States
California
Maryland
Washington
Canada
Brazil
South Korea1
Japan
Taiwan
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE2
Saudi Arabia2
Qatar2
Oman2
Kuwait2
Bahrain2
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe4 regulations
European UnionBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: EC 1223/2009 Annex II

European UnionRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: EC 1223/2009 Annex III

United KingdomBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: UK retained EC 1223/2009 Annex II

United KingdomRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
Max: 0,5 % To be printed on the label: Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘ black henna ’ tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary ‘ black henna ’ tattoo in the past. Hair colorants can cause severe allergic reactions.
Other conditions
Do not use with nitrosating agents Maximum nitrosamine content: 50 μg/kg Keep in nitrite-free containers

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania1 regulation
South KoreaBannedAnnex banned #M836
Chemical name
Hydroxyanthraquinone-Aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5

Source: MFDS Korea Cosmetics Regulation

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #308
Chemical name
1-N-Methylmorpholiniumpropylamino-4- hydroxyanthraquinone, methyl sulfate Hydroxyanthraquinone-aminopropyl Methyl Morpholinium Methosulfate
CAS
38866-20-5
Max concentration
0.5%
Product type
Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
-Do not use with nitrosating agents -Maximum nitrosamine content: 50 μg/kg (21) -Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: To be printed on the label: ' Hair colorants can cause severe allergic reactions Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: -you have a rash on your face or sensitive, irritated and damaged scalp, -you have ever experienced any reaction after colouring your hair, -you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC12 regulations
UAEBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

UAERestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

Saudi ArabiaRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

QatarRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

OmanRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

KuwaitRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainBannedAnnex II #344
Chemical name
Morpholine and its salts
CAS
110-91-8

Source: GSO 1943:2024 (based on EU 1223/2009 II)

BahrainRestrictedAnnex III #293
Chemical name
1-N-Methylmorpholiniumpropylamino-4-hydroxyanthraquinone, methyl sulfate
CAS
38866-20-5
Max concentration
0,5 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
To be printed on the label: “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, —you have experienced a reaction to a temporary “black henna” tattoo in the past.”
Other conditions
—Do not use with nitrosating agents —Maximum nitrosamine content: 50 μg/kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE banned in any country?

Yes, HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE is banned in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Always check current regulations before formulating products for these markets.

What are the restrictions on HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE in cosmetics?

HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE in cosmetics?

HYDROXYANTHRAQUINONEAMINOPROPYL METHYL MORPHOLINIUM METHOSULFATE is regulated in 15 markets. It is banned in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. It has restrictions in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.