HEXETIDINE

RestrictedCAS 141-94-622 regulations across 22 markets

HEXETIDINE is a cosmetic ingredient classified as Antimicrobial. Also known as CAS 141-94-6. It is regulated in 22 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number
141-94-6

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil1
South Korea1
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia1
Belarus1
Kazakhstan1
Armenia1
Kyrgyzstan1

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #19
Chemical name
5- Pyrimidinamine, 1,3-bis (2-ethylhexyl) hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0,1 %
Conditions of use
Max: 0,1 %

Source: UK retained EC 1223/2009 Annex V

Americas1 regulation
BrazilRestrictedAnnex RDC_528 #18
Chemical name
Amino-5-bis(etil-2- hexil)-1,3 metil-5-perhidropir imidina
CAS
141-94-6
Max concentration
0,1%

Source: ANVISA RDC 528

East Asia & Oceania2 regulations
South KoreaRestrictedAnnex restricted #M1247
Chemical name
Hexetidine
Conditions of use
* 배합한도 : ∙ 사용 후 씻어내는 제품에 0.1% ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Preservatives List #25
Chemical name
5-Pyrimidinamine, 1,3-bis (2-ethylhexyl) hexahydro-5-methyl
CAS
141-94-6
Max concentration
0.1 %

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex VI (Preservatives) #19
Chemical name
Hexetidine (INN)
CAS
141-94-6
Max concentration
0.1%

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

Saudi ArabiaRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

QatarRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

OmanRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

KuwaitRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

BahrainRestrictedAnnex V #19
Chemical name
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
CAS
141-94-6
Max concentration
0.1%

Source: GSO 1943:2024 (based on EU 1223/2009 V)

EAEU5 regulations
RussiaRestrictedAnnex 4 #19
Chemical name
5-пиримидин, 1,3-бис(2-этилгексил)гексагидро-5-метил- (5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-metyl-)
CAS
141-94-6
Max concentration
0,1 процента

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 19)

BelarusRestrictedAnnex 4 #19
Chemical name
5-пиримидин, 1,3-бис(2-этилгексил)гексагидро-5-метил- (5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-metyl-)
CAS
141-94-6
Max concentration
0,1 процента

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 19)

KazakhstanRestrictedAnnex 4 #19
Chemical name
5-пиримидин, 1,3-бис(2-этилгексил)гексагидро-5-метил- (5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-metyl-)
CAS
141-94-6
Max concentration
0,1 процента

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 19)

ArmeniaRestrictedAnnex 4 #19
Chemical name
5-пиримидин, 1,3-бис(2-этилгексил)гексагидро-5-метил- (5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-metyl-)
CAS
141-94-6
Max concentration
0,1 процента

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 19)

KyrgyzstanRestrictedAnnex 4 #19
Chemical name
5-пиримидин, 1,3-бис(2-этилгексил)гексагидро-5-метил- (5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-metyl-)
CAS
141-94-6
Max concentration
0,1 процента

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 19)

Frequently Asked Questions

Is HEXETIDINE banned in any country?

HEXETIDINE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on HEXETIDINE in cosmetics?

HEXETIDINE is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use HEXETIDINE in cosmetics?

HEXETIDINE is regulated in 22 markets. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.