DIHYDROXYINDOLINE HBR

RestrictedCAS 138937-28-710 regulations across 10 markets

DIHYDROXYINDOLINE HBR is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 138937-28-7. It is regulated in 10 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
138937-28-7

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea1
Japan
Taiwan1
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt
CAS
29539-03-5 / 138937-28-7
Max concentration
2,0 %
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
Max: 2,0 % Can cause allergic reaction

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for DIHYDROXYINDOLINE HBR in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania2 regulations
South KoreaRestrictedAnnex restricted #M838
Chemical name
Dihydroxyindoline HBr

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Restricted Ingredients List #137
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt
CAS
29539-03-5/ 138937-28-7
Max concentration
2%
Product type
Non-oxidative hair dye products

Source: TFDA Cosmetics Regulations

ASEANNo restrictions

No specific restrictions for DIHYDROXYINDOLINE HBR in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAERestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #204
Chemical name
2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
CAS
29539-03-5 - 138937-28-7
Max concentration
2.0%
Product type
Hair dye substance in non-oxidative hair dye products
Conditions of use
- Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for DIHYDROXYINDOLINE HBR in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is DIHYDROXYINDOLINE HBR banned in any country?

DIHYDROXYINDOLINE HBR is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on DIHYDROXYINDOLINE HBR in cosmetics?

DIHYDROXYINDOLINE HBR is restricted or has conditions of use in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use DIHYDROXYINDOLINE HBR in cosmetics?

DIHYDROXYINDOLINE HBR is regulated in 10 markets. It has restrictions in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.