CI 45396

RestrictedCAS 24545-86-621 regulations across 21 markets

CI 45396 is a cosmetic ingredient classified as Colorant. Also known as CAS 24545-86-6. It is regulated in 21 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number: 24545-86-6

Market Overview — 29 Markets

European Union1

United Kingdom1

United States

California

Maryland

Washington

Canada

Brazil1

South Korea

Japan

Taiwan1

Australia

Singapore1

Malaysia1

Thailand1

Indonesia1

Vietnam1

Philippines1

UAE1

Saudi Arabia1

Qatar1

Oman1

Kuwait1

Bahrain1

Russia1

Belarus1

Kazakhstan1

Armenia1

Kyrgyzstan1

Detailed Regulations

Europe2 regulations

European UnionRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: EC 1223/2009 Annex IV

United KingdomRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 %, when used in lip products
Conditions of use: Max: 1 %, when used in lip products
Other conditions: Only in free acid form, when used in lip products
Color Index: 45396

Source: UK retained EC 1223/2009 Annex IV

Americas1 regulation

BrazilRestrictedAnnex RDC_628 #CI_45396

Product type: products_in_general
Conditions of use: Application fields: products_in_general | Limitations: Concentração máxima em produtos para lábios na forma ácida livre: 1%
Color Index: CI 45396

Source: ANVISA RDC 628

East Asia & Oceania1 regulation

TaiwanRestrictedAnnex Colorants List #75

Chemical name: CI 45396
Product type: Scope 1: All cosmetic products
Conditions of use: Using in lip products: the limited content is 1%, and shall be used in free acid form.
Color Index: CI 45396

Source: TFDA Cosmetics Regulations

ASEAN6 regulations

SingaporeRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex IV (Colorants) #45396

Chemical name: Orange
Max concentration: When used in lipstick, the colouring agent is allowed only in free acid form and in a maximum concentration of 1%
Product type: All cosmetic products
Color Index: CI 45396

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations

UAERestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

Saudi ArabiaRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

QatarRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

OmanRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

KuwaitRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

BahrainRestrictedAnnex IV #77

Chemical name: 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
CAS: 24545-86-6
Max concentration: 1%
Conditions of use: Only in free acid form, when used in lip products
Other conditions: when used in lip products
Color Index: CI 45396

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

EAEU5 regulations

RussiaRestrictedAnnex 3 #77

Chemical name: 3',6'-дигидрокси-4',5'-динитроспиро[изобензофуран-1(3H),9'-[9H]ксантен]-3-он 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 процент, при использовании в продуктах для губ
Other conditions: только в виде свободной кислоты при использовании в продуктах для губ
Color Index: 45396

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 77)

BelarusRestrictedAnnex 3 #77

Chemical name: 3',6'-дигидрокси-4',5'-динитроспиро[изобензофуран-1(3H),9'-[9H]ксантен]-3-он 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 процент, при использовании в продуктах для губ
Other conditions: только в виде свободной кислоты при использовании в продуктах для губ
Color Index: 45396

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 77)

KazakhstanRestrictedAnnex 3 #77

Chemical name: 3',6'-дигидрокси-4',5'-динитроспиро[изобензофуран-1(3H),9'-[9H]ксантен]-3-он 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 процент, при использовании в продуктах для губ
Other conditions: только в виде свободной кислоты при использовании в продуктах для губ
Color Index: 45396

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 77)

ArmeniaRestrictedAnnex 3 #77

Chemical name: 3',6'-дигидрокси-4',5'-динитроспиро[изобензофуран-1(3H),9'-[9H]ксантен]-3-он 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 процент, при использовании в продуктах для губ
Other conditions: только в виде свободной кислоты при использовании в продуктах для губ
Color Index: 45396

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 77)

KyrgyzstanRestrictedAnnex 3 #77

Chemical name: 3',6'-дигидрокси-4',5'-динитроспиро[изобензофуран-1(3H),9'-[9H]ксантен]-3-он 3',6'-Dihydroxy-4',5'-dinitrospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
Max concentration: 1 процент, при использовании в продуктах для губ
Other conditions: только в виде свободной кислоты при использовании в продуктах для губ
Color Index: 45396

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 77)

Frequently Asked Questions

Is CI 45396 banned in any country?

CI 45396 is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on CI 45396 in cosmetics?

CI 45396 is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use CI 45396 in cosmetics?

CI 45396 is regulated in 21 markets. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.