CI 45220

RestrictedCAS 5873-16-521 regulations across 21 markets

CI 45220 is a cosmetic ingredient classified as Colorant. Also known as CAS 5873-16-5. It is regulated in 21 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number
5873-16-5

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil1
South Korea
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia1
Belarus1
Kazakhstan1
Armenia1
Kyrgyzstan1

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: EC 1223/2009 Annex IV

United KingdomRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
Product type
Rinse-off products
Color Index
45220

Source: UK retained EC 1223/2009 Annex IV

Americas1 regulation
BrazilRestrictedAnnex RDC_628 #CI_45220
Product type
brief_contact_only
Conditions of use
Application fields: brief_contact_only
Color Index
CI 45220

Source: ANVISA RDC 628

East Asia & Oceania1 regulation
TaiwanRestrictedAnnex Colorants List #71
Chemical name
CI 45220
Product type
Scope 4: Cosmetic products intended to come into contact only briefly with the skin
Color Index
CI 45220

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex IV (Colorants) #45220
Chemical name
Red
Product type
Products with brief skin contact only
Color Index
CI 45220

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

Saudi ArabiaRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

QatarRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

OmanRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

KuwaitRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

BahrainRestrictedAnnex IV #73
Chemical name
Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethylxanthylium, monosodium salt
CAS
5873-16-5
Product type
Rinse-off products
Color Index
CI 45220

Source: GSO 1943:2024 (based on EU 1223/2009 IV)

EAEU5 regulations
RussiaRestrictedAnnex 3 #73
Chemical name
Водород 9-(2,4-дисульфонатфенил)-3,6-бис(этиламино)-2,7-диметил-ксантилиум, мононатриевая соль Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-xanthylium, monosodium salt
Product type
смываемая продукция
Color Index
45220

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 73)

BelarusRestrictedAnnex 3 #73
Chemical name
Водород 9-(2,4-дисульфонатфенил)-3,6-бис(этиламино)-2,7-диметил-ксантилиум, мононатриевая соль Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-xanthylium, monosodium salt
Product type
смываемая продукция
Color Index
45220

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 73)

KazakhstanRestrictedAnnex 3 #73
Chemical name
Водород 9-(2,4-дисульфонатфенил)-3,6-бис(этиламино)-2,7-диметил-ксантилиум, мононатриевая соль Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-xanthylium, monosodium salt
Product type
смываемая продукция
Color Index
45220

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 73)

ArmeniaRestrictedAnnex 3 #73
Chemical name
Водород 9-(2,4-дисульфонатфенил)-3,6-бис(этиламино)-2,7-диметил-ксантилиум, мононатриевая соль Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-xanthylium, monosodium salt
Product type
смываемая продукция
Color Index
45220

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 73)

KyrgyzstanRestrictedAnnex 3 #73
Chemical name
Водород 9-(2,4-дисульфонатфенил)-3,6-бис(этиламино)-2,7-диметил-ксантилиум, мононатриевая соль Hydrogen 9-(2,4-disulphonatophenyl)-3,6-bis(ethylamino)-2,7-dimethyl-xanthylium, monosodium salt
Product type
смываемая продукция
Color Index
45220

Source: TR CU 009/2011 Annex 3 (Colorants) (Ref 73)

Frequently Asked Questions

Is CI 45220 banned in any country?

CI 45220 is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on CI 45220 in cosmetics?

CI 45220 is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use CI 45220 in cosmetics?

CI 45220 is regulated in 21 markets. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.