CHLORHEXIDINE DIHYDROCHLORIDE
CHLORHEXIDINE DIHYDROCHLORIDE is a cosmetic ingredient classified as Antimicrobial. Also known as CAS 3697-42-5. It is regulated in 12 markets including UAE, Bahrain, Canada.
Also Known As
- CAS Number
- 18472-51-0, 3697-42-5, 55-56-1, 56-95-1
Market Overview — 29 Markets
Detailed Regulations
Europe2 regulations
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: EC 1223/2009 Annex V
- Chemical name
- N,N″-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1, 56-95-1, 18472-51-0, 3697-42-5
- Max concentration
- 0,3 % (as chlorhexidine)
- Conditions of use
- Max: 0,3 % (as chlorhexidine)
Source: UK retained EC 1223/2009 Annex V
Americas1 regulation
- Chemical name
- Chlorhexidine and its salts
- CAS
- 3697-42-5
- Max concentration
- a) 0.14% calculated as chlorhexidine free base
- Conditions of use
- b) 0.19% calculated as chlorhexidine diacetate c) 0.20% calculated as chlorhexidine digluconate d) 0.16% calculated as chlorhexidine dihydrochloride
Source: Health Canada Cosmetic Ingredient Hotlist
East Asia & Oceania4 regulations
- Chemical name
- Chlorhexidine Dihydrochloride
- Conditions of use
- * 배합한도 : ∙ 점막에 사용하지 않고 씻어내는 제품에 클로헥시딘으로서 0.1%, ∙ 기타 제품에 클로헥시딘으로서 0.05%
Source: MFDS Korea Cosmetics Regulation
- Chemical name
- Chlorhexidine hydrochloride
- Max concentration
- 0.10%
- Product type
- Leave-on (cosmetics not washed away)
Source: MHLW Standards for Cosmetics (Notification No.331 of 2000)
- Chemical name
- Chlorhexidine hydrochloride
- Max concentration
- 0.10%
- Product type
- Rinse-off (cosmetics washed away after use)
Source: MHLW Standards for Cosmetics (Notification No.331 of 2000)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazat-etradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1/ 18472-51-0/ 3697-42-5 56-95-1/
- Max concentration
- 0.3 % (以 chlorhexidine計)
Source: TFDA Cosmetics Regulations
ASEANNo restrictions
No specific restrictions for CHLORHEXIDINE DIHYDROCHLORIDE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.
GCC6 regulations
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
- Chemical name
- N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine and its digluconate, diacetate and dihydrochloride
- CAS
- 55-56-1 / 56-95-1 / 18472-51-0 / 3697-42-5
- Max concentration
- 0.3% (as chlorhexidine)
Source: GSO 1943:2024 (based on EU 1223/2009 V)
EAEUNo restrictions
No specific restrictions for CHLORHEXIDINE DIHYDROCHLORIDE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is CHLORHEXIDINE DIHYDROCHLORIDE banned in any country?
CHLORHEXIDINE DIHYDROCHLORIDE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on CHLORHEXIDINE DIHYDROCHLORIDE in cosmetics?
CHLORHEXIDINE DIHYDROCHLORIDE is restricted or has conditions of use in UAE, Bahrain, Canada, European Union, Japan, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use CHLORHEXIDINE DIHYDROCHLORIDE in cosmetics?
CHLORHEXIDINE DIHYDROCHLORIDE is regulated in 12 markets. It has restrictions in UAE, Bahrain, Canada, European Union, Japan, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
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Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.