CALCIUM THIOGLYCOLATE HYDROXIDE

RestrictedCAS 65208-41-512 regulations across 9 markets

CALCIUM THIOGLYCOLATE HYDROXIDE is a cosmetic ingredient classified as Depilatory. Also known as CAS 65208-41-5. It is regulated in 9 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
68-11-1, 29820-13-1, 65208-41-5

Market Overview — 29 Markets

European Union1
United Kingdom4
United States
California
Maryland
Washington
Canada
Brazil
South Korea1
Japan
Taiwan
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe5 regulations
European UnionRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
68-11-1
Max concentration
(a) 8 % 11 %
Product type
(a) Hair waving or straightening products
Conditions of use
Max: (a) 8 % 11 % Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions
Other conditions
(a) General use ready for use pH 7 to 9,5 Professional use ready for use pH 7 to 9,5

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
68-11-1
Max concentration
(b) 5 %
Product type
(b) Depilatories
Conditions of use
Max: (b) 5 % Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions
Other conditions
(b) ready for use pH 7 to 12,7

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
68-11-1
Max concentration
(c) 2 %
Product type
(c) Other hair rinse-off products
Conditions of use
Max: (c) 2 % Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions
Other conditions
(c) ready for use pH 7 to 9,5

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
68-11-1
Max concentration
(d) 11 % The abovementioned percentages are calculated as thioglycolic acid
Product type
(d) Products intended for eyelash waving
Conditions of use
Max: (d) 11 % The abovementioned percentages are calculated as thioglycolic acid Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions
Other conditions
(d) For professional use ready for use pH 7 to 9,5

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for CALCIUM THIOGLYCOLATE HYDROXIDE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania1 regulation
South KoreaRestrictedAnnex restricted #M1290
Chemical name
Calcium Thioglycolate Hydroxide
Conditions of use
* 배합한도 : ∙ 퍼머넌트웨이브용 및 헤어스트레이트너 제품에 치오글라이콜릭애씨드로서 11% (다만, 가온2욕식 헤어스트레이트너 제품의 경우에는 치오글라이콜릭애씨드로서 5%, 치오글라이콜릭애씨드 및 그 염류를 주성분으로 하고 제1제 사용 시 조제하는 발열 2욕식 퍼머넌트웨이브용 제품의 경우 치오글라이콜릭애씨드로서 19%에 해당하는 양) ∙ 제모용 제품에 치오글라이콜릭애씨드로서 5% ∙ 염모제에 치오글라이콜릭애씨드로서 1% ∙ 사용 후 씻어내는 두발용 제품류에 2% ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

ASEANNo restrictions

No specific restrictions for CALCIUM THIOGLYCOLATE HYDROXIDE in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAERestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #2a
Chemical name
Thioglycolic acid and its salts
CAS
65208-41-5
Max concentration
(a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
Product type
(a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Conditions of use
Conditions of use: (a) (b) (c) (d) Avoid contact with eyes Rinse eyes immediately if product comes into contact with them. (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a)(i) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a)(ii) (d) For professional use only Contains thioglycolate Follow the instructions’
Other conditions
(a) (i) General use ready for use pH 7 to 9.5 (ii) Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for CALCIUM THIOGLYCOLATE HYDROXIDE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is CALCIUM THIOGLYCOLATE HYDROXIDE banned in any country?

CALCIUM THIOGLYCOLATE HYDROXIDE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on CALCIUM THIOGLYCOLATE HYDROXIDE in cosmetics?

CALCIUM THIOGLYCOLATE HYDROXIDE is restricted or has conditions of use in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use CALCIUM THIOGLYCOLATE HYDROXIDE in cosmetics?

CALCIUM THIOGLYCOLATE HYDROXIDE is regulated in 9 markets. It has restrictions in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.