BENZOPHENONE-4

RestrictedCAS 4065-45-621 regulations across 21 markets

BENZOPHENONE-4 is a cosmetic ingredient classified as Light Stabilizer. Also known as CAS 4065-45-6. It is regulated in 21 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number: 6628-37-1, 4065-45-6

Market Overview — 29 Markets

European Union1

United Kingdom1

United States

California

Maryland

Washington

Canada

Brazil1

South Korea1

Japan

Taiwan

Australia

Singapore1

Malaysia1

Thailand1

Indonesia1

Vietnam1

Philippines1

UAE1

Saudi Arabia1

Qatar1

Oman1

Kuwait1

Bahrain1

Russia1

Belarus1

Kazakhstan1

Armenia1

Kyrgyzstan1

Detailed Regulations

Europe2 regulations

European UnionRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: EC 1223/2009 Annex VI

United KingdomRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone
CAS: 4065-45-6/6628-37-1
Max concentration: 5 % (as acid)
Conditions of use: Max: 5 % (as acid)

Source: UK retained EC 1223/2009 Annex VI

Americas1 regulation

BrazilRestrictedAnnex RDC_600 #13

Chemical name: Ácido 2 - hidroxi - 4 - metoxibenzofenona - 5 - sulfônico BENZOPHENONE-4 (ACID)
Max concentration: 10% (expresso como ácido)

Source: ANVISA RDC 600

East Asia & Oceania1 regulation

South KoreaRestrictedAnnex restricted #M1369

Chemical name: Benzophenone-4
Conditions of use: * 배합한도 : 5%

Source: MFDS Korea Cosmetics Regulation

ASEAN6 regulations

SingaporeRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex VII (UV Filters) #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-4) and its sodium salt (Benzophenone-5) / Benzophenone-4Benzophenone-5
CAS: 4065-45-6
Max concentration: 5% (as acid)

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations

UAERestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

Saudi ArabiaRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

QatarRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

OmanRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

KuwaitRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

BahrainRestrictedAnnex VI #22

Chemical name: 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid (Benzophenone-5) and its sodium salt / Sulisobenzone
CAS: 4065-45-6 / 6628-37-1
Max concentration: 5%(as acid)

Source: GSO 1943:2024 (based on EU 1223/2009 VI)

EAEU5 regulations

RussiaRestrictedAnnex 5 #22

Chemical name: 2-Гидрокси-4-метоксибензо-фенон-5-сульфоновая кислота и ее натриевые соли /Сулисобензон (2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone)
CAS: 4065-45-6/6628-37-1
Max concentration: 5 процентов (в пересчете на кислоту)

Source: TR CU 009/2011 Annex 5 (UV Filters) (Ref 22)

BelarusRestrictedAnnex 5 #22

Chemical name: 2-Гидрокси-4-метоксибензо-фенон-5-сульфоновая кислота и ее натриевые соли /Сулисобензон (2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone)
CAS: 4065-45-6/6628-37-1
Max concentration: 5 процентов (в пересчете на кислоту)

Source: TR CU 009/2011 Annex 5 (UV Filters) (Ref 22)

KazakhstanRestrictedAnnex 5 #22

Chemical name: 2-Гидрокси-4-метоксибензо-фенон-5-сульфоновая кислота и ее натриевые соли /Сулисобензон (2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone)
CAS: 4065-45-6/6628-37-1
Max concentration: 5 процентов (в пересчете на кислоту)

Source: TR CU 009/2011 Annex 5 (UV Filters) (Ref 22)

ArmeniaRestrictedAnnex 5 #22

Chemical name: 2-Гидрокси-4-метоксибензо-фенон-5-сульфоновая кислота и ее натриевые соли /Сулисобензон (2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone)
CAS: 4065-45-6/6628-37-1
Max concentration: 5 процентов (в пересчете на кислоту)

Source: TR CU 009/2011 Annex 5 (UV Filters) (Ref 22)

KyrgyzstanRestrictedAnnex 5 #22

Chemical name: 2-Гидрокси-4-метоксибензо-фенон-5-сульфоновая кислота и ее натриевые соли /Сулисобензон (2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid and its sodium salt/Sulisobenzone)
CAS: 4065-45-6/6628-37-1
Max concentration: 5 процентов (в пересчете на кислоту)

Source: TR CU 009/2011 Annex 5 (UV Filters) (Ref 22)

Frequently Asked Questions

Is BENZOPHENONE-4 banned in any country?

BENZOPHENONE-4 is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on BENZOPHENONE-4 in cosmetics?

BENZOPHENONE-4 is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use BENZOPHENONE-4 in cosmetics?

BENZOPHENONE-4 is regulated in 21 markets. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.