ANETHOLE

BannedCAS 104-46-114 regulations across 14 markets

ANETHOLE is a cosmetic ingredient classified as Denaturant. Also known as CAS 104-46-1. It is regulated in 14 markets including UAE, Bahrain, Brazil.

Also Known As

CAS Number
4180-23-8, 104-46-1

Market Overview — 29 Markets

European Union1
United Kingdom
United States
California
Maryland
Washington
Canada
Brazil1
South Korea
Japan
Taiwan
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe1 regulation
European UnionRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: EC 1223/2009 Annex III

Americas1 regulation
BrazilBannedAnnex RDC_529 #47
Chemical name
Benzeno
CAS
71-43-2

Source: ANVISA RDC 529

East Asia & OceaniaNo restrictions

No specific restrictions for ANETHOLE in South Korea, Japan, Taiwan, Australia.

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #329
Chemical name
11,14-Dioxa-2,9- diazaheptadec-16- enoic Acid, 4,4,6,16- tetramethyl- 10,15- dioxo, 2-[(2-methyl- 1-oxo-2- propenyl) oxy]ethyl ester DI-HEMA TRIMETHYLHEXYL DICARBAMATE 41137-60-4/ 72869-86-4
Max concentration
Professional use only
Product type
Nail Products
Conditions of use
For professional use only Can cause an allergic reaction

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #329
Chemical name
1-Methoxy-4-(1E)- 1-propen-1-yl- benzene (trans- Anethole)
CAS
104-46-1/ 4180-23-8
Other conditions
The presence of the substance shall be indicated in the list of ingredients referred to in Article 19(1), point (g), when its concentration exceeds: — 0,001 % in leave-on products — 0,01 % in rinse-off products.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for ANETHOLE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is ANETHOLE banned in any country?

Yes, ANETHOLE is banned in Brazil. Always check current regulations before formulating products for these markets.

What are the restrictions on ANETHOLE in cosmetics?

ANETHOLE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use ANETHOLE in cosmetics?

ANETHOLE is regulated in 14 markets. It is banned in Brazil. It has restrictions in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.