ALPHA-ARBUTIN

RestrictedCAS 84380-01-88 regulations across 8 markets

ALPHA-ARBUTIN is a cosmetic ingredient classified as Antioxidant. Also known as CAS 84380-01-8. It is regulated in 8 markets including UAE, Australia, Bahrain.

Also Known As

CAS Number
84380-01-8

Market Overview — 29 Markets

European Union1
United Kingdom
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan
Australia1
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe1 regulation
European UnionRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for ALPHA-ARBUTIN in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania1 regulation
AustraliaRestrictedAnnex Schedule 6 (Poison) #SUSMP Schedule 6
Chemical name
ARBUTIN (ALPHA) except
Conditions of use
(a) in preparations for application to the face containing 2% or less alpha-arbutin with hydroquinone levels of 10mg/kg or less; or (b) in preparations for application to the body containing 0.5% or less alpha-arbutin with hydroquinone levels of 10mg/kg or less.

Source: TGA SUSMP F2026L00060

ASEANNo restrictions

No specific restrictions for ALPHA-ARBUTIN in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC6 regulations
UAERestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #377
Chemical name
4-Hydroxyphenyl-alpha-D-glucopyranoside
CAS
84380-01-8
Max concentration
(a) 2 % (b) 0,5 %
Product type
(a) Face cream (b) Body lotion
Other conditions
Hydroquinone levels shall remain as low as possible in formulations containing alpha-Arbutin and shall not be higher than the unavoidable trace level. From 1 February 2025 cosmetic products containing that substance and not complying with the conditions shall not be placed on the Union market. From 1 November 2025 cosmetic products containing that substance and not complying with the conditions shall not be made available on the Union market.

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for ALPHA-ARBUTIN in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is ALPHA-ARBUTIN banned in any country?

ALPHA-ARBUTIN is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on ALPHA-ARBUTIN in cosmetics?

ALPHA-ARBUTIN is restricted or has conditions of use in UAE, Australia, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use ALPHA-ARBUTIN in cosmetics?

ALPHA-ARBUTIN is regulated in 8 markets. It has restrictions in UAE, Australia, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.