4-NITRO-O-PHENYLENEDIAMINE
RestrictedCAS 99-56-916 regulations across 16 markets
4-NITRO-O-PHENYLENEDIAMINE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 99-56-9. It is regulated in 16 markets including UAE, Bahrain, European Union.
Also Known As
- CAS Number
- 99-56-9
Market Overview — 29 Markets
European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea1
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan
Detailed Regulations
Europe2 regulations
European UnionRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: EC 1223/2009 Annex III
United KingdomRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %
Source: UK retained EC 1223/2009 Annex III
AmericasNo restrictions
No specific restrictions for 4-NITRO-O-PHENYLENEDIAMINE in United States, California, Maryland, Washington, Canada, Brazil.
East Asia & Oceania2 regulations
South KoreaRestricted
- Chemical name
- 4-Nitro-o-Phenylenediamine
- Conditions of use
- * 배합한도 : ∙ 산화염모제에 1.5 % ∙ 기타 제품에는 사용금지
Source: MFDS Korea Cosmetics Regulation
TaiwanRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Max concentration
- 0.5%
- Product type
- Oxidative hair dye products
Source: TFDA Cosmetics Regulations
ASEAN6 regulations
SingaporeRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
MalaysiaRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
ThailandRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
IndonesiaRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
VietnamRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
PhilippinesRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine / 4-Nitro-o-Phenylenediamine
- CAS
- 99-56-9
- Max concentration
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% Indonesia only : After mixing under oxidative conditions the maximum concentration applied to hai
- Product type
- Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
GCC6 regulations
UAERestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
Saudi ArabiaRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
QatarRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
OmanRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
KuwaitRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
BahrainRestricted
- Chemical name
- 4-Nitro-1,2-phenylenediamine
- CAS
- 99-56-9
- Product type
- Hair dye substance in oxidative hair dye products
- Conditions of use
- To be printing on the label: Hair colorants can cause severe allergic reactions.
- Other conditions
- After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5%
Source: GSO 1943:2024 (based on EU 1223/2009 III)
EAEUNo restrictions
No specific restrictions for 4-NITRO-O-PHENYLENEDIAMINE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is 4-NITRO-O-PHENYLENEDIAMINE banned in any country?
4-NITRO-O-PHENYLENEDIAMINE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on 4-NITRO-O-PHENYLENEDIAMINE in cosmetics?
4-NITRO-O-PHENYLENEDIAMINE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use 4-NITRO-O-PHENYLENEDIAMINE in cosmetics?
4-NITRO-O-PHENYLENEDIAMINE is regulated in 16 markets. It has restrictions in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
Screen 4-NITRO-O-PHENYLENEDIAMINE with your full formula
Paste your entire ingredient list and get a compliance report across 26 markets — free, no signup.
Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.