4-HYDROXYPROPYLAMINO-3-NITROPHENOL

RestrictedCAS 92952-81-321 regulations across 10 markets

4-HYDROXYPROPYLAMINO-3-NITROPHENOL is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 92952-81-3. It is regulated in 10 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
92952-81-3

Market Overview — 29 Markets

European Union2
United Kingdom3
United States
California
Maryland
Washington
Canada
Brazil
South Korea3
Japan
Taiwan1
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE2
Saudi Arabia2
Qatar2
Oman2
Kuwait2
Bahrain2
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe5 regulations
European UnionRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: EC 1223/2009 Annex III

European UnionRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #205
Chemical name
See 219

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene
CAS
92952-81-3
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions.
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): Do not use with nitrosating agents Maximum nitrosamine content: 50 μg /kg Keep in nitrite-free containers

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(b) Hair dye substance in non-oxidative hair dye products
Conditions of use
Max: (b) 2,6 % (a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions.
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): Do not use with nitrosating agents Maximum nitrosamine content: 50 μg /kg Keep in nitrite-free containers

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for 4-HYDROXYPROPYLAMINO-3-NITROPHENOL in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania4 regulations
South KoreaRestrictedAnnex restricted #M420
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene
CAS
92952-81-3

Source: MFDS Korea Cosmetics Regulation

South KoreaRestrictedAnnex restricted #M567
Chemical name
4-Hydroxypropylamino-3-Nitrophenol
Conditions of use
* 배합한도 : 2.6% 염모용 화장품에만 사용

Source: MFDS Korea Cosmetics Regulation

South KoreaRestrictedAnnex restricted #M62
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene and its salts (e.g. 4-Hydroxypropylamino-3-nitrophenol) (with the exception that the maximum use concentration applied to hair must not exceed 2.6%)
CAS
92952-81-3

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Restricted Ingredients List #112
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene
CAS
92952-81-3
Max concentration
(a)2.6% (b)2.6%
Product type
(a)Oxidative hair dye products (b)Non-oxidative hair dye products
Conditions of use
Prohibited to use with nitrosating agents; Maximum nitrosamine content: 50 mg/kg(ppb); Must be stored in a nitrite free container.

Source: TFDA Cosmetics Regulations

ASEANNo restrictions

No specific restrictions for 4-HYDROXYPROPYLAMINO-3-NITROPHENOL in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC12 regulations
UAERestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

UAERestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #205
Chemical name
1-Hydroxy-3-nitro-4-(3-hydroxypropylamino)benzene (see note 17)
CAS
92952-81-3
Max concentration
(b) 2.6%
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.
Other conditions
(a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #219
Chemical name
1-Hydroxy-3-nitro- 4-(3-hydroxypropy lamino)benzene
CAS
92952-81-3
Max concentration
(b) 2,6 %
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,6 % calculated as free base. For (a) and (b): — Do not use with nitro sating agents — Maximum nitrosamine content: 50 μg /kg — Keep in nitrite-free containers

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for 4-HYDROXYPROPYLAMINO-3-NITROPHENOL in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is 4-HYDROXYPROPYLAMINO-3-NITROPHENOL banned in any country?

4-HYDROXYPROPYLAMINO-3-NITROPHENOL is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on 4-HYDROXYPROPYLAMINO-3-NITROPHENOL in cosmetics?

4-HYDROXYPROPYLAMINO-3-NITROPHENOL is restricted or has conditions of use in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use 4-HYDROXYPROPYLAMINO-3-NITROPHENOL in cosmetics?

4-HYDROXYPROPYLAMINO-3-NITROPHENOL is regulated in 10 markets. It has restrictions in UAE, Bahrain, European Union, South Korea, Kuwait, Oman, Qatar, Saudi Arabia, Taiwan, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

Screen 4-HYDROXYPROPYLAMINO-3-NITROPHENOL with your full formula

Paste your entire ingredient list and get a compliance report across 26 markets — free, no signup.

Check Ingredients Free

This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.