2-METHYL-5-HYDROXYETHYLAMINOPHENOL

RestrictedCAS 55302-96-019 regulations across 16 markets

2-METHYL-5-HYDROXYETHYLAMINOPHENOL is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 55302-96-0. It is regulated in 16 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number: 55302-96-0

Market Overview — 29 Markets

European Union1

United Kingdom2

United States

California

Maryland

Washington

Canada

Brazil

South Korea3

Japan

Taiwan1

Australia

Singapore1

Malaysia1

Thailand1

Indonesia1

Vietnam1

Philippines1

UAE1

Saudi Arabia1

Qatar1

Oman1

Kuwait1

Bahrain1

Russia

Belarus

Kazakhstan

Armenia

Kyrgyzstan

Detailed Regulations

Europe3 regulations

European UnionRestrictedAnnex III #229

Chemical name: 5-[(2-hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0
Product type: (a) Hair dye substance in oxidatie hair dye products. (b) Products intended for colouring eyelashes
Conditions of use: (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (b) To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes,
Other conditions: For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,5% - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #229

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0
Product type: (a) Hair dye substance in oxidative hair dye products
Conditions of use: (a) To be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colorants can cause severe allergic reactions.
Other conditions: For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,5 % Do not use with nitrosating agents Maximum nitrosamine content: 50 μg /kg Keep in nitrite-free containers

Source: UK retained EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #229

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0
Product type: (b) Products intended for colouring eyelashes
Conditions of use: (b) To be printed on the label: The mixing ratio. For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: has a rash on the face or sensitive, irritated and damaged scalp, has experienced any reaction after colouring hair or eyelashes, has experienced a reaction to a temporary “ black henna ” tattoo in the past. Rinse eyes immediately if product comes into contact with them.
Other conditions: (b) For professional use only.

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for 2-METHYL-5-HYDROXYETHYLAMINOPHENOL in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania4 regulations

South KoreaRestrictedAnnex restricted #M141

Chemical name: 5-[(2-hydroxyethyl)amino]-o-cresol and its salt (e.g. 2-Methyl-5-Hydroxyethylaminophenol) (with the exception of 2-Methyl-5-Hydroxyethylaminophenol as the hair dye substance that the maximum use concentration applied to hair must not exceed 0.5%)
CAS: 55302-96-0

Source: MFDS Korea Cosmetics Regulation

South KoreaRestrictedAnnex restricted #M21

Chemical name: 2-Methyl-5-Hydroxyethylaminophenol
Conditions of use: * 배합한도 : ∙ 산화염모제에 0.5 % ∙ 기타 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

South KoreaRestrictedAnnex restricted #M501

Chemical name: 5-[(2-hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Restricted Ingredients List #74

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0
Max concentration: 1.5%
Product type: Oxidative hair dye products
Conditions of use: Prohibited to use with nitrosating agents; Maximum nitrosamine content: 50 mg/kg(ppb); Must be stored in a nitrite free container.

Source: TFDA Cosmetics Regulations

ASEAN6 regulations

SingaporeRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #232

Chemical name: 5-[(2-Hydroxyethyl)amino]-o-cresol / 2-Methyl-5-hydroxyethylaminophenol
CAS: 55302-96-0
Max concentration: After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5% • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitri
Product type: Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use: The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary 'black henna' tattoo in the past Do not use to dye eyelashes or eyebrows

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations

UAERestrictedAnnex III #229

Chemical name: 5-[(2-hydroxyethyl)amino]-o-cresol
CAS: 55302-96-0
Product type: (a) Hair dye substance in oxidatie hair dye products. (b) Products intended for colouring eyelashes
Conditions of use: (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (b) To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes,
Other conditions: For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 1,5% - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers