2-HYDROXYETHYLAMINO-5-NITROANISOLE
2-HYDROXYETHYLAMINO-5-NITROANISOLE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 66095-81-6. It is regulated in 16 markets including UAE, Bahrain, European Union.
Also Known As
- CAS Number
- 66095-81-6
Market Overview — 29 Markets
Detailed Regulations
Europe2 regulations
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: EC 1223/2009 Annex III
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0,2 %
- Product type
- Hair dye substance in non-oxidative hair dye products
- Conditions of use
- Max: 0,2 %
- Other conditions
- Do not use with nitrosating agents Maximum nitrosamine content: 50 μg /kg Keep in nitrite-free containers
Source: UK retained EC 1223/2009 Annex III
AmericasNo restrictions
No specific restrictions for 2-HYDROXYETHYLAMINO-5-NITROANISOLE in United States, California, Maryland, Washington, Canada, Brazil.
East Asia & Oceania2 regulations
- Chemical name
- 2-Hydroxyethylamino-5-Nitroanisole
Source: MFDS Korea Cosmetics Regulation
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Non-oxidative hair dye products
- Conditions of use
- Prohibited to use with nitrosating agents; Maximum nitrosamine content: 50 mg/kg(ppb); Must be stored in a nitrite free container.
Source: TFDA Cosmetics Regulations
ASEAN6 regulations
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
- Chemical name
- 2-[(2-methoxy-4- nitrophenyl)amino]ethanol and its salts 2-Hydroxyethylamino- 5-nitroanisole
- CAS
- 66095-81-6
- Max concentration
- 0.2%
- Product type
- Hair dye substance in non- oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Conditions of use
- • Do not use with nitrosating agents • Maximum nitrosamine content: 50 μg/kg (21) • Keep in nitrite-free containers The direction for use 'wear suitable gloves' must be included in label or leaflet text. | Label: Do not use to dye eyelashes or eyebrows
Source: ASEAN Cosmetic Directive (HSA Dec 2025)
GCC6 regulations
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
- Chemical name
- 2-[(2-methoxy-4-nitrophenyl)amino]ethanol and its salts
- CAS
- 66095-81-6
- Max concentration
- 0.2%%
- Product type
- Hair dye substance in non-oxidative hair dye products
- Other conditions
- - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Source: GSO 1943:2024 (based on EU 1223/2009 III)
EAEUNo restrictions
No specific restrictions for 2-HYDROXYETHYLAMINO-5-NITROANISOLE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.
Frequently Asked Questions
Is 2-HYDROXYETHYLAMINO-5-NITROANISOLE banned in any country?
2-HYDROXYETHYLAMINO-5-NITROANISOLE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.
What are the restrictions on 2-HYDROXYETHYLAMINO-5-NITROANISOLE in cosmetics?
2-HYDROXYETHYLAMINO-5-NITROANISOLE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.
Can I use 2-HYDROXYETHYLAMINO-5-NITROANISOLE in cosmetics?
2-HYDROXYETHYLAMINO-5-NITROANISOLE is regulated in 16 markets. It has restrictions in UAE, Bahrain, European Union, Indonesia, South Korea, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.
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Check Ingredients FreeThis information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.