2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE

BannedCAS 50610-28-110 regulations across 9 markets

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 50610-28-1. It is regulated in 9 markets including Indonesia, South Korea, Malaysia.

Also Known As

CAS Number
50610-28-1

Market Overview — 29 Markets

European Union
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea2
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE
Saudi Arabia
Qatar
Oman
Kuwait
Bahrain
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe1 regulation
United KingdomBannedAnnex II #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts, when used as a substance in hair dye products
CAS
50610-28-1

Source: UK retained EC 1223/2009 Annex II

AmericasNo restrictions

No specific restrictions for 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & Oceania3 regulations
South KoreaBannedAnnex banned #M364
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1

Source: MFDS Korea Cosmetics Regulation

South KoreaBannedAnnex banned #M83
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-Phenylenediamine

Source: MFDS Korea Cosmetics Regulation

TaiwanBannedAnnex Prohibited Ingredients List #289
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl- p-phenylenediamine and its salts 不得使用於染髮用途化粧品
CAS
50610-28-1

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesBannedAnnex ACD Annex II (Prohibited) #1318
Chemical name
2-Chloro-5-nitro-N-hydroxyethyl-p-phenylenediamine and its salts
CAS
50610-28-1
Product type
hair dye products

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCCNo restrictions

No specific restrictions for 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE in UAE, Saudi Arabia, Qatar, Oman, Kuwait, Bahrain.

EAEUNo restrictions

No specific restrictions for 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE banned in any country?

Yes, 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE is banned in Indonesia, South Korea, Malaysia, Philippines, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Always check current regulations before formulating products for these markets.

What are the restrictions on 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE in cosmetics?

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE is banned in Indonesia, South Korea, Malaysia, Philippines, Singapore, Thailand, Taiwan, United Kingdom, Vietnam and has no specific restrictions in other tracked markets.

Can I use 2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE in cosmetics?

2-CHLORO-5-NITRO-N-HYDROXYETHYL-P-PHENYLENEDIAMINE is regulated in 9 markets. It is banned in Indonesia, South Korea, Malaysia, Philippines, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.