2-BROMO-2-NITROPROPANE-1,3-DIOL

BannedCAS 52-51-724 regulations across 24 markets

2-BROMO-2-NITROPROPANE-1,3-DIOL is a cosmetic ingredient classified as Preservative. Also known as CAS 52-51-7. It is regulated in 24 markets including UAE, Armenia, Bahrain.

Also Known As

CAS Number
52-51-7

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington1
Canada1
Brazil1
South Korea1
Japan
Taiwan1
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia1
Belarus1
Kazakhstan1
Armenia1
Kyrgyzstan1

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: EC 1223/2009 Annex V

United KingdomRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0,1 %
Conditions of use
Max: 0,1 %
Other conditions
Avoid formation of nitrosamines

Source: UK retained EC 1223/2009 Annex V

Americas3 regulations
WashingtonBannedAnnex HB1047_P2
Chemical name
2-Bromo-2-Nitropropane-1,3-Diol (Bronopol)
CAS
52-51-7
Conditions of use
Banned effective 2027-01-01 (HB 1047 Phase 2 - formaldehyde releasers)

Source: WA HB 1047 (Toxic-Free Cosmetics Act)

CanadaRestrictedAnnex Table 2 (Restricted)
Chemical name
2-Bromo-2-nitropropane-1,3-diol
CAS
52-51-7
Max concentration
b) 0.1%
Conditions of use
a) Not permitted in cosmetics that contain amines or amides. b) Other cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

BrazilRestrictedAnnex RDC_528 #20
Chemical name
2-bromo-2-nitropr opano-1,3-diol (Bronopol)
CAS
52-51-7
Max concentration
0,1%
Conditions of use
Limitations: Evitar formação de nitrosamina s.

Source: ANVISA RDC 528

East Asia & Oceania2 regulations
South KoreaRestrictedAnnex restricted #M1172
Chemical name
2-Bromo-2-Nitropropane-1,3-Diol
Conditions of use
* 배합한도 : 0.10% 아민류나 아마이드류를 함유하고 있는 제품에는 사용금지

Source: MFDS Korea Cosmetics Regulation

TaiwanRestrictedAnnex Preservatives List #50
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1 %
Conditions of use
Avoid formation of nitrosamines; When used as preservatives in cosmetic products, the total amount of released free formaldehyde should not exceed 1000 ppm

Source: TFDA Cosmetics Regulations

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex VI (Preservatives) #21
Chemical name
Bronopol (INN)
CAS
52-51-7
Max concentration
0.1%
Conditions of use
Avoid formation of nitrosamines

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

Saudi ArabiaRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

QatarRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

OmanRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

KuwaitRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

BahrainRestrictedAnnex V #21
Chemical name
Bronopol
CAS
52-51-7
Max concentration
0.1%
Other conditions
Avoid formation of nitrosamines

Source: GSO 1943:2024 (based on EU 1223/2009 V)

EAEU5 regulations
RussiaRestrictedAnnex 4 #21
Chemical name
Бронопол (Bronopol)
CAS
52-51-7
Max concentration
0,1 процента
Other conditions
может способствовать образованию нитрозаминов

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 21)

BelarusRestrictedAnnex 4 #21
Chemical name
Бронопол (Bronopol)
CAS
52-51-7
Max concentration
0,1 процента
Other conditions
может способствовать образованию нитрозаминов

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 21)

KazakhstanRestrictedAnnex 4 #21
Chemical name
Бронопол (Bronopol)
CAS
52-51-7
Max concentration
0,1 процента
Other conditions
может способствовать образованию нитрозаминов

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 21)

ArmeniaRestrictedAnnex 4 #21
Chemical name
Бронопол (Bronopol)
CAS
52-51-7
Max concentration
0,1 процента
Other conditions
может способствовать образованию нитрозаминов

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 21)

KyrgyzstanRestrictedAnnex 4 #21
Chemical name
Бронопол (Bronopol)
CAS
52-51-7
Max concentration
0,1 процента
Other conditions
может способствовать образованию нитрозаминов

Source: TR CU 009/2011 Annex 4 (Preservatives) (Ref 21)

Frequently Asked Questions

Is 2-BROMO-2-NITROPROPANE-1,3-DIOL banned in any country?

Yes, 2-BROMO-2-NITROPROPANE-1,3-DIOL is banned in Washington. Always check current regulations before formulating products for these markets.

What are the restrictions on 2-BROMO-2-NITROPROPANE-1,3-DIOL in cosmetics?

2-BROMO-2-NITROPROPANE-1,3-DIOL is restricted or has conditions of use in UAE, Armenia, Bahrain, Brazil, Belarus, Canada, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use 2-BROMO-2-NITROPROPANE-1,3-DIOL in cosmetics?

2-BROMO-2-NITROPROPANE-1,3-DIOL is regulated in 24 markets. It is banned in Washington. It has restrictions in UAE, Armenia, Bahrain, Brazil, Belarus, Canada, European Union, Indonesia, Kyrgyzstan, South Korea, Kuwait, Kazakhstan, Malaysia, Oman, Philippines, Qatar, Russia, Saudi Arabia, Singapore, Thailand, Taiwan, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.