2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE

RestrictedCAS 1603-02-714 regulations across 14 markets

2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE is a cosmetic ingredient classified as Hair Dyeing. Also known as CAS 1603-02-7. It is regulated in 14 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
1603-02-7

Market Overview — 29 Markets

European Union1
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan
Australia
Singapore1
Malaysia1
Thailand1
Indonesia1
Vietnam1
Philippines1
UAE1
Saudi Arabia1
Qatar1
Oman1
Kuwait1
Bahrain1
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe2 regulations
European UnionRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6-triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018 , to be printed on the label: The mixing ratio. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “ black henna ” tattoos may increase your risk of allergy. Do not colour your hair if: you have a rash on your face or sensitive, irritated and damaged scalp, you have ever experienced any reaction after colouring your hair, you have experienced a reaction to a temporary “ black henna ” tattoo in the past. Hair colourants can cause severe allergic reactions.
Other conditions
As from 3 September 2017 , after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & OceaniaNo restrictions

No specific restrictions for 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE in South Korea, Japan, Taiwan, Australia.

ASEAN6 regulations
SingaporeRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

MalaysiaRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

ThailandRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

IndonesiaRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

VietnamRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

PhilippinesRestrictedAnnex ACD Annex III (Restricted) #317
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate 2,5,6-Triamino- 4-Pyrimidinol sulfate
CAS
1603-02-7
Max concentration
After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.5% The direction for use 'wear suitable gloves' must be included in label or leaflet text.
Product type
Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
Conditions of use
To be printed on the label: 'Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary 'black henna' tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary 'black henna' tattoo in the past. Do not use to dye eyelashes or eyebrows.'

Source: ASEAN Cosmetic Directive (HSA Dec 2025)

GCC6 regulations
UAERestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #301
Chemical name
4-Hydroxy-2,5,6- triaminopyrimidine sulfate
CAS
1603-02-7
Product type
Hair dye substance in oxidative hair dye products
Conditions of use
As from 3 March 2018, to be printed on the label: The mixing ratio. ‘ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’
Other conditions
As from 3 September 2017, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,5 %

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE banned in any country?

2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE in cosmetics?

2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE is restricted or has conditions of use in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use 2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE in cosmetics?

2,5,6-TRIAMINO-4-PYRIMIDINOL SULFATE is regulated in 14 markets. It has restrictions in UAE, Bahrain, European Union, Indonesia, Kuwait, Malaysia, Oman, Philippines, Qatar, Saudi Arabia, Singapore, Thailand, United Kingdom, Vietnam. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.