1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL

RestrictedCAS 74918-21-115 regulations across 8 markets

1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL is a cosmetic ingredient classified as Not Reported. Also known as CAS 74918-21-1. It is regulated in 8 markets including UAE, Bahrain, European Union.

Also Known As

CAS Number
74918-21-1, 81892-72-0

Market Overview — 29 Markets

European Union2
United Kingdom1
United States
California
Maryland
Washington
Canada
Brazil
South Korea
Japan
Taiwan
Australia
Singapore
Malaysia
Thailand
Indonesia
Vietnam
Philippines
UAE2
Saudi Arabia2
Qatar2
Oman2
Kuwait2
Bahrain2
Russia
Belarus
Kazakhstan
Armenia
Kyrgyzstan

Detailed Regulations

Europe3 regulations
European UnionRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: EC 1223/2009 Annex III

European UnionRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: EC 1223/2009 Annex III

United KingdomRestrictedAnnex III #202
Chemical name
See 226

Source: UK retained EC 1223/2009 Annex III

AmericasNo restrictions

No specific restrictions for 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in United States, California, Maryland, Washington, Canada, Brazil.

East Asia & OceaniaNo restrictions

No specific restrictions for 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in South Korea, Japan, Taiwan, Australia.

ASEANNo restrictions

No specific restrictions for 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in Singapore, Malaysia, Thailand, Indonesia, Vietnam, Philippines.

GCC12 regulations
UAERestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

UAERestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

Saudi ArabiaRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

QatarRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

OmanRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

KuwaitRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #202
Chemical name
4,4'-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt (see note 17)
CAS
81892-72-0 - 74918-21-1
Product type
(a) Hair dye substance in oxidative hair dye products
Conditions of use
(a) The mixing ratio: Hair colorants can cause severe allergic reactions. (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.2% calculated as free base (1.8% as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

BahrainRestrictedAnnex III #226
Chemical name
4,4′-[1,3-Propanediylbis(oxy)]bisbenzene-1,3-diamine and its tetrahydrochloride salt
CAS
81892-72-0 / 74918-21-1
Max concentration
(b) 1,2 % as free base (1,8 % as tetrahydrochloride salt)
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Conditions of use
(a) To be printed on the label: The mixing ratio. ‘imageHair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ (b) Can cause allergic reaction
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,2 % calculated as free base (1,8 % as tetrahydrochloride salt).

Source: GSO 1943:2024 (based on EU 1223/2009 III)

EAEUNo restrictions

No specific restrictions for 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in Russia, Belarus, Kazakhstan, Armenia, Kyrgyzstan.

Frequently Asked Questions

Is 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL banned in any country?

1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL is not banned in any of the 26 markets tracked by Formpli. However, it may be subject to restrictions or conditions of use in some markets.

What are the restrictions on 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in cosmetics?

1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL is restricted or has conditions of use in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Restrictions may include maximum concentration limits, product type limitations, or mandatory labeling requirements. See the detailed regulations above for specifics.

Can I use 1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL in cosmetics?

1,3-BIS-(2,4-DIAMINOPHENOXY) PROPANE HCL is regulated in 8 markets. It has restrictions in UAE, Bahrain, European Union, Kuwait, Oman, Qatar, Saudi Arabia, United Kingdom. Use Formpli's free screening tool to check your full ingredient list against all 26 markets at once.

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This information is for reference only and does not constitute legal or regulatory advice. Regulations change — always verify with official sources and consult a regulatory specialist before exporting cosmetic products. Data sourced from EU COSING, US FDA, Health Canada, MHLW Japan, MFDS Korea, ASEAN ACD, GCC SFDA, TGA Australia, ANVISA Brazil, EAEU TR CU, and Taiwan TFDA.